• Stable from pH 1-13
• No Organic Solvents Required for Separation
• Rigid Polymer Backbone
• Available in PEEK or Stainless Steel Column Formats

Premier C3 and Phenyl hydrophobic interaction columns (HIC) contain porous hydrophilic rigid polymer packings that have been bonded with either alkyl (C3) or phenyl groups. They are stable in the pH range of 1-13 and are compatible with most organic solvents.

Hydrophobic Interaction Chromatography (HIC) separates proteins by mechanisms similar to reversed phase chromatography but under gentle reverse salt gradient elution conditions in aqueous buffers. Biological activity of the analyte remains generally intact since no organic solvents are used.