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GX-281 Analytical-to-Semipreparative HPLC System

The GX-281 features a large bed capacity within only 35” of linear bench space. The revolutionary Solvent System is offered in a Preparative and Analytical versions providing flow rate and volume options ranging from nLs to 100s of mLs. The innovative GX Z-injection technology offers ideal injection performance for volumes ranging from uL to mL ranges with minimal extra volume. Gilson’s 15X Series UV/VIS detectors offer an interchangeable flow cell design making it suitable for applications ranging from analytical to semi-preparative flow rates. Add on the new prepELS Detector to any Gilson analytical or semi-preparative system for increased detection capabilities of any compounds or impurities lacking chromophores.

GX Z-injection Technology
GX Z-Injection Module features fast, low carryover /maintenance injections by aspirating the sample directly into the valve.

Low Mount Fraction Collection
Separate injection and fraction collection pathways eliminate contamination of fractions from sample injection.

GX-281 Liquid Handler
A single instrument for high throughput injection, fraction collection and re-injection – no need to transfer tubes or racks to another system.

Semipreparative Pumping Solutions

  • 305 Pump - 10 µL/min-200 mL/min flow rate with up to 8,700 psi (600 bar) pressure.
  • 306 Pump - 10 µL/min-200 mL/min flow rate with up to 8,700 psi (600 bar) pressure.
  • 307 Pump - 10 µL/min-10 mL/min flow rate with up to 8,700 psi (600 bar) pressure.
  • 321 Pump - 150 µL/min-15 mL/min flow rate with 8,700 psi (600 bar) pressure.
  • 322 Pumps - 300 µL/min-30 mL/min flow rate with 4,350 psi (300 bar) pressure.
  • 331/332 Pumps - 0.5-50 mL/min flow rate with 8,700 psi (600 bar) pressure.

prepELS™ Detector

  • Add the new prepELS Detector to any Gilson semipreparative purification system for detecting impurities and compounds of interest not found by UV detection alone.
  • Precisely controlled spray chamber and drift tube temperature with patented Thermo- Split Technology allows for optimization of the detector signal whether running gradient or isocratic conditions.

Sample Loading Capacity

Up to 300 mg/injection

Optimal Column Size

2.0-20 mm

Flow Rate

H1: 0.15-15; H2: 0.3-30 mL/min

Injection Volume

2 µL-25 mL

Maximum Injection Pressure

5,000 psi (345 bar)

Maximum Pump Pressure

H1: 8,700 psi (600 bar); H2: 4,350 psi (300 bar)

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