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GX-281 Preparative HPLC System

The GX-281 features a large bed capacity that uses only 35” of linear bench space. The revolutionary GX Prep Solvent System features flow rates up to 50 mL/min and volumes ranging from µLs to 100s of mLs. The GX-281 offers numerous injection options ranging from our innovative GX Z-injection Module which aspirates sample directly into the valve to our GX Direct Injection Module which features the largest range of injection volumes available in the market today. The GX-281 truly is the next evolution in front end HPLC automation.

GX Z-Injection Module
The GX Z-Injection module is the industry leading injection technology. Sample is aspirated directly into the injection valve reducing carryover and plugging issues from standard injection ports, decreasing cycle times and reducing sample waste.

Automated Column Selection
Automatic selection of up to 6 different columns allows for purifying a wide range of sample masses and allows for automated use of several different column chemistries without modifying system hardware.

Low Mount Fraction Collection

  • Fraction Collection at flow rates up to 200 mL/min.
  • Separate Injection and collection pathways eliminates contamination of fractions from the injection process.

GX Prep Solvent System
The GX Prep Solvent System features volume capabilities ranging from 50 µL to 100s of mLs and flow rates up to 50 mL/min. The solvent valve allows for immediate access of up to 5 off bed solvent reservoirs.

GX Direct Injection Module
The GX Direct Injection Module is compatible with both the GX-271 and GX-281 Liquid Handlers.
It features an innovative injection port design that attaches directly to the injection valve reducing void volumes and minimizing carryover associated with calibrated connection tubing. The GX Direct Injection Module offers sample loops sizes ranging from 2 µL to 25 mL providing the largest sample volume range in the market today.

System Overview

Sample Loading Capacity

Up to 15 g/injection

Optimal Column Size

10–100 mm

Flow Rate

1.0–200 mL/min

Injection Volume

250 µL–25 mL

Maximum Injection Pressure

5,000 psi (345 bar)

Maximum Pump Pressure

3,040 psi (210 bar)

GX-281 Liquid Handler Tube Capacities

Tube Diameter

Tube Capacity

13 mm

576

15 mm

576

16 mm

450

18 mm

420

25 mm

180

28 mm

162

Note: The GX-281 can accommodate test tubes up to 220 mm tall

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